S87314-10mg Morinidazole 92478-27-8 98% 10mg 5000.00 现货

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产品描述： Morinidazole shows antibacterial activity and can be used in studies about bacterial infections research such as appendicitis and pelvic inflammatory disease caused by anaerobic bacteria.
靶点： Antibacterial
体外研究： Morinidazole shows antibacterial activity against Trichomonas vaginalis and Entamoeba histolytica with MICs of 2 and 3 μg/mL
体内研究： Morinidazole (20 and 25 mg/kg; p.o.) inhibits Trichomonas vaginalis and Entamoeba histolytica in vivo[2]. In the renal failure model in SD rats, Morinidazole (50 mg/kg; i.v.) shows a higher concentration in the liver, plasma, and kidney than lung, spleen, and heart
参考文献：
1. Zhong K, et al. Effects of renal impairment on the pharmacokinetics of morinidazole: uptake transporter-mediated renal clearanceof the conjugated metabolites. Antimicrob Agents Chemother. 2014 Jul;58(7):4153-61. 2. Lu Aifeng, et al. Application of α-(morpholine-1-yl)methyl-2-methyl-nitroimidazole-1-ethanol as anti-trichomonal agent and amebacide: China, CN1981764[P]. 2007-06-20. 3. Kong F, et al. Increased Plasma Exposures of Conjugated Metabolites of Morinidazole in Renal Failure Patients: A Critical Role of Uremic Toxins. Drug Metab Dispos. 2017 Jun;45(6):593-603.
溶解性： Soluble in DMSO
保存条件： -20℃
配置溶液浓度参考：

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